Cargando…

Endogenous Myelin Basic Protein Inactivates the High Avidity T Cell Repertoire

To study the contribution of endogenous myelin basic protein (MBP) to the positive and/or negative selection of the MBP-specific T cell repertoire, we studied the T cell response to MBP in MBP-deficient shiverer and MBP-expressing congenic C3H mice. Immunization with MBP induced a vigorous T cell re...

Descripción completa

Detalles Bibliográficos
Autores principales: Targoni, Oleg S., Lehmann, Paul V.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212353/
https://www.ncbi.nlm.nih.gov/pubmed/9625765