Extrathymic T Cell Deletion and Allogeneic Stem Cell Engraftment Induced with Costimulatory Blockade Is Followed by Central T Cell Tolerance

A reliable, nontoxic method of inducing transplantation tolerance is needed to overcome the problems of chronic organ graft rejection and immunosuppression-related toxicity. Treatment of mice with single injections of an anti-CD40 ligand antibody and CTLA4Ig, a low dose (3 Gy) of whole body irradiat...

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Detalles Bibliográficos
Autores principales: Wekerle, Thomas, Sayegh, Mohamed H., Hill, Joshua, Zhao, Yong, Chandraker, Anil, Swenson, Kirsten G., Zhao, Guiling, Sykes, Megan
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212372/
https://www.ncbi.nlm.nih.gov/pubmed/9625763

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212372/
https://www.ncbi.nlm.nih.gov/pubmed/9625763

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