Human Toll-like Receptor 2 Confers Responsiveness to Bacterial Lipopolysaccharide

Bacterial lipopolysaccharide (LPS) induces activation of the transcription factor nuclear factor κB (NF-κB) in host cells upon infection. LPS binds to the glycosylphosphatidylinositol (GPI)- anchored membrane protein CD14, which lacks an intracellular signaling domain. Here we investigated the role...

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Detalles Bibliográficos
Autores principales: Kirschning, Carsten J., Wesche, Holger, Merrill Ayres, T., Rothe, Mike
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212382/
https://www.ncbi.nlm.nih.gov/pubmed/9841923

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212382/
https://www.ncbi.nlm.nih.gov/pubmed/9841923

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