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A Caspase-activated Factor (CAF) Induces Mitochondrial Membrane Depolarization and Cytochrome c Release by a Nonproteolytic Mechanism

It is well established that apoptosis is accompanied by activation of procaspases and by mitochondrial changes, such as decrease in mitochondrial transmembrane potential (ΔΨ(m)) and release of cytochrome c. We analyzed the causal relationship between activated caspases and these mitochondrial phenom...

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Detalles Bibliográficos
Autores principales: Steemans, Margino, Goossens, Vera, Van de Craen, Marc, Van Herreweghe, Franky, Vancompernolle, Katia, De Vos, Kurt, Vandenabeele, Peter, Grooten, Johan
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212395/
https://www.ncbi.nlm.nih.gov/pubmed/9841933