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Overexpression of Natural Killer T Cells Protects Vα14-Jα281 Transgenic Nonobese Diabetic Mice against Diabetes

Progression to destructive insulitis in nonobese diabetic (NOD) mice is linked to the failure of regulatory cells, possibly involving T helper type 2 (Th2) cells. Natural killer (NK) T cells might be involved in diabetes, given their deficiency in NOD mice and the prevention of diabetes by adoptive...

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Detalles Bibliográficos
Autores principales: Lehuen, Agnès, Lantz, Olivier, Beaudoin, Lucie, Laloux, Véronique, Carnaud, Claude, Bendelac, Albert, Bach, Jean-François, Monteiro, Renato C.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212408/
https://www.ncbi.nlm.nih.gov/pubmed/9815260