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Permanent CD8(+) T Cell Depletion Prevents Proteinuria in Active Heymann Nephritis

Active Heymann nephritis (HN) is a rat model of human idiopathic membranous nephropathy in which injury is thought to be mediated by membrane attack complex of complement (MAC) activated by antibody (Ab) to glomerular epithelial cells. Recent work has shown that HN develops in C6-deficient rats whic...

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Detalles Bibliográficos
Autores principales: Penny, Mark J., Boyd, Rochelle A., Hall, Bruce M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212409/
https://www.ncbi.nlm.nih.gov/pubmed/9815255