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Development of a Natural Model of Cutaneous Leishmaniasis: Powerful Effects of  Vector Saliva and Saliva Preexposure on the Long-Term Outcome of Leishmania major Infection in the Mouse Ear Dermis

We have developed a model of cutaneous leishmaniasis due to Leishmania major that seeks to mimic the natural conditions of infection. 1,000 metacyclic promastigotes were coinoculated with a salivary gland sonicate (SGS) obtained from a natural vector, Phlebotomus papatasii, into the ear dermis of na...

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Detalles Bibliográficos
Autores principales: Belkaid, Yasmine, Kamhawi, Shaden, Modi, Govind, Valenzuela, Jesus, Noben-Trauth, Nancy, Rowton, Edgar, Ribeiro, José, Sacks, David L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212417/
https://www.ncbi.nlm.nih.gov/pubmed/9815271