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Development of a Natural Model of Cutaneous Leishmaniasis: Powerful Effects of Vector Saliva and Saliva Preexposure on the Long-Term Outcome of Leishmania major Infection in the Mouse Ear Dermis
We have developed a model of cutaneous leishmaniasis due to Leishmania major that seeks to mimic the natural conditions of infection. 1,000 metacyclic promastigotes were coinoculated with a salivary gland sonicate (SGS) obtained from a natural vector, Phlebotomus papatasii, into the ear dermis of na...
Autores principales: | Belkaid, Yasmine, Kamhawi, Shaden, Modi, Govind, Valenzuela, Jesus, Noben-Trauth, Nancy, Rowton, Edgar, Ribeiro, José, Sacks, David L. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1998
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212417/ https://www.ncbi.nlm.nih.gov/pubmed/9815271 |
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