Interleukin 6 Influences Germinal Center Development and Antibody Production via a Contribution of C3 Complement Component

Mice rendered deficient for interleukin (IL) 6 by gene targeting were evaluated for their response to T cell–dependent antigens. Antigen-specific immunoglobulin (Ig)M levels were unaffected whereas all IgG isotypes showed varying degrees of alteration. Germinal center reactions occurred but remained...

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Detalles Bibliográficos
Autores principales: Kopf, Manfred, Herren, Suzanne, Wiles, Michael V., Pepys, Mark B., Kosco-Vilbois, Marie H.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212418/
https://www.ncbi.nlm.nih.gov/pubmed/9815267

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212418/
https://www.ncbi.nlm.nih.gov/pubmed/9815267

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