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Viral Immune Evasion Due to Persistence of Activated T Cells Without Effector Function

We examined the regulation of virus-specific CD8 T cell responses during chronic lymphocytic choriomeningitis virus (LCMV) infection of mice. Our study shows that within the same persistently infected host, different mechanisms can operate to silence antiviral T cell responses; CD8 T cells specific...

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Detalles Bibliográficos
Autores principales: Zajac, Allan J., Blattman, Joseph N., Murali-Krishna, Kaja, Sourdive, David J.D., Suresh, M., Altman, John D., Ahmed, Rafi
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212420/
https://www.ncbi.nlm.nih.gov/pubmed/9858507