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Contribution of  Virus-specific CD8(+) Cytotoxic T Cells to Virus Clearance or Pathologic Manifestations of Influenza Virus Infection in a T Cell Receptor Transgenic Mouse Model

The ability of influenza virus to evade immune surveillance by neutralizing antibodies (Abs) directed against its variable surface antigens provides a challenge to the development of effective vaccines. CD8(+) cytotoxic T lymphocytes (CTLs) restricted by class I major histocompatibility complex mole...

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Detalles Bibliográficos
Autores principales: Moskophidis, Demetrius, Kioussis, Dimitris
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212460/
https://www.ncbi.nlm.nih.gov/pubmed/9670035