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The Vav–Rac1 Pathway in Cytotoxic Lymphocytes Regulates the Generation of Cell-mediated Killing

The Rac1 guanine nucleotide exchange factor, Vav, is activated in hematopoietic cells in response to a large variety of stimuli. The downstream signaling events derived from Vav have been primarily characterized as leading to transcription or transformation. However, we report here that Vav and Rac1...

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Detalles Bibliográficos
Autores principales: Billadeau, Daniel D., Brumbaugh, Kathryn M., Dick, Christopher J., Schoon, Renee A., Bustelo, Xose R., Leibson, Paul J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212464/
https://www.ncbi.nlm.nih.gov/pubmed/9687532