Cargando…
The Vav–Rac1 Pathway in Cytotoxic Lymphocytes Regulates the Generation of Cell-mediated Killing
The Rac1 guanine nucleotide exchange factor, Vav, is activated in hematopoietic cells in response to a large variety of stimuli. The downstream signaling events derived from Vav have been primarily characterized as leading to transcription or transformation. However, we report here that Vav and Rac1...
Autores principales: | Billadeau, Daniel D., Brumbaugh, Kathryn M., Dick, Christopher J., Schoon, Renee A., Bustelo, Xose R., Leibson, Paul J. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1998
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212464/ https://www.ncbi.nlm.nih.gov/pubmed/9687532 |
Ejemplares similares
-
The Rho Family Guanine Nucleotide Exchange Factor Vav-2 Regulates the Development of Cell-Mediated Cytotoxicity
por: Billadeau, Daniel D., et al.
Publicado: (2000) -
Functional Role for Syk Tyrosine Kinase in Natural Killer Cell–mediated Natural Cytotoxicity
por: Brumbaugh, Kathryn M., et al.
Publicado: (1997) -
Vav family exchange factors: an integrated regulatory and functional view
por: Bustelo, Xosé R
Publicado: (2014) -
Lysine Acetylation Reshapes the Downstream Signaling Landscape of Vav1 in Lymphocytes
por: Rodríguez-Fdez, Sonia, et al.
Publicado: (2020) -
A Balance between Positive and Negative Signals in Cytotoxic Lymphocytes Regulates the Polarization of Lipid Rafts during the Development of Cell-Mediated Killing
por: Lou, Zhenkun, et al.
Publicado: (2000)