Transgenic Mice Overexpressing the Complement Inhibitor Crry as a Soluble Protein Are Protected from Antibody-induced Glomerular Injury

Complement receptor 1–related gene/protein y (Crry) is a potent murine membrane complement regulator that inhibits classical and alternative pathway C3 convertases. In nephrotoxic serum (NTS) nephritis, injected antibodies (Abs) bind to glomeruli, leading to complement activation and subsequent glom...

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Detalles Bibliográficos
Autores principales: Quigg, Richard J., He, Chun, Lim, Alice, Berthiaume, Dawn, Alexander, Jessy J., Kraus, Damian, Michael Holers, V.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212499/
https://www.ncbi.nlm.nih.gov/pubmed/9763611

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212499/
https://www.ncbi.nlm.nih.gov/pubmed/9763611

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