Cargando…
Transgenic Mice Overexpressing the Complement Inhibitor Crry as a Soluble Protein Are Protected from Antibody-induced Glomerular Injury
Complement receptor 1–related gene/protein y (Crry) is a potent murine membrane complement regulator that inhibits classical and alternative pathway C3 convertases. In nephrotoxic serum (NTS) nephritis, injected antibodies (Abs) bind to glomeruli, leading to complement activation and subsequent glom...
Autores principales: | Quigg, Richard J., He, Chun, Lim, Alice, Berthiaume, Dawn, Alexander, Jessy J., Kraus, Damian, Michael Holers, V. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1998
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212499/ https://www.ncbi.nlm.nih.gov/pubmed/9763611 |
Ejemplares similares
-
Structures of the rat complement regulator CrrY
por: Roversi, Pietro, et al.
Publicado: (2011) -
Expression of Membrane Complement Regulatory Proteins Crry and CD55 in Normal Rats
por: Kato, Chie, et al.
Publicado: (2013) -
Crry silencing alleviates Alzheimer’s disease injury by regulating neuroinflammatory cytokines and the complement system
por: Zhu, Xi-Chen, et al.
Publicado: (2022) -
C2 IgM Natural Antibody Enhances Inflammation and Its Use in the Recombinant Single Chain Antibody-Fused Complement Inhibitor C2-Crry to Target Therapeutics to Joints Attenuates Arthritis in Mice
por: Banda, Nirmal K., et al.
Publicado: (2020) -
Complement inhibitor Crry expression in mouse placenta is essential for maintaining normal blood pressure and fetal growth
por: Banadakoppa, Manu, et al.
Publicado: (2020)