Human Immunoglobulin (Ig)M(+)IgD(+) Peripheral Blood B Cells Expressing the CD27 Cell Surface Antigen Carry Somatically Mutated Variable Region Genes: CD27 as a General Marker for Somatically Mutated (Memory) B Cells

Immunoglobulin (Ig)M(+)IgD(+) B cells are generally assumed to represent antigen-inexperienced, naive B cells expressing variable (V) region genes without somatic mutations. We report here that human IgM(+)IgD(+) peripheral blood (PB) B cells expressing the CD27 cell surface antigen carry mutated V...

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Detalles Bibliográficos
Autores principales: Klein, Ulf, Rajewsky, Klaus, Küppers, Ralf
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212515/
https://www.ncbi.nlm.nih.gov/pubmed/9802980

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212515/
https://www.ncbi.nlm.nih.gov/pubmed/9802980

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