Cargando…

Potent T Cell Activation with Dimeric Peptide–Major Histocompatibility Complex Class II Ligand: The Role of CD4 Coreceptor

The interaction of the T cell receptor (TCR) with its cognate peptide–major histocompatibility complex (MHC) on the surface of antigen presenting cells (APCs) is a primary event during T cell activation. Here we used a dimeric IE(k)-MCC molecule to study its capacity to activate antigen-specific T c...

Descripción completa

Detalles Bibliográficos
Autores principales: Hamad, Abdel Rahim A., O'Herrin, Sean M., Lebowitz, Michael S., Srikrishnan, Ananth, Bieler, Joan, Schneck, Jonathan, Pardoll, Drew
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212519/
https://www.ncbi.nlm.nih.gov/pubmed/9802975