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An Essential Role for Tumor Necrosis Factor in Natural Killer Cell–mediated Tumor Rejection in the Peritoneum

Natural killer (NK) cells are thought to provide the first line of defence against tumors, particularly major histocompatibility complex (MHC) class I(−) variants. We have confirmed in C57BL/6 (B6) mice lacking perforin that peritoneal growth of MHC class I(−) RMA-S tumor cells in unprimed mice is c...

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Detalles Bibliográficos
Autores principales: Smyth, Mark J., Kelly, Janice M., Baxter, Alan G., Körner, Heinrich, Sedgwick, Jonathon D.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212521/
https://www.ncbi.nlm.nih.gov/pubmed/9802973