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Differential expression of the FAK family kinases in rheumatoid arthritis and osteoarthritis synovial tissues
The focal adhesion kinase (FAK) family kinases, including FAK and proline-rich kinase 2 (Pyk)2, are the predominant mediators of integrin αvβ3 signaling events that play an important role in cell adhesion, osteoclast pathology, and angiogenesis, all processes important in rheumatoid arthritis (RA)....
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212559/ https://www.ncbi.nlm.nih.gov/pubmed/17963503 http://dx.doi.org/10.1186/ar2318 |