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Differential expression of the FAK family kinases in rheumatoid arthritis and osteoarthritis synovial tissues

The focal adhesion kinase (FAK) family kinases, including FAK and proline-rich kinase 2 (Pyk)2, are the predominant mediators of integrin αvβ3 signaling events that play an important role in cell adhesion, osteoclast pathology, and angiogenesis, all processes important in rheumatoid arthritis (RA)....

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Detalles Bibliográficos
Autores principales: Shahrara, Shiva, Castro-Rueda, Hernan P, Haines, G Kenneth, Koch, Alisa E
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212559/
https://www.ncbi.nlm.nih.gov/pubmed/17963503
http://dx.doi.org/10.1186/ar2318