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Analysis of C4 and the C4 binding protein in the MRL/lpr mouse

Systemic lupus erythematosus is a complement-mediated autoimmune disease. While genetic deficiencies of classical pathway components lead to an increased risk of developing systemic lupus erythematosus, end organ damage is associated with complement activation and immune complex deposition. The role...

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Detalles Bibliográficos
Autores principales: Wenderfer, Scott E, Soimo, Kipruto, Wetsel, Rick A, Braun, Michael C
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212569/
https://www.ncbi.nlm.nih.gov/pubmed/17971229
http://dx.doi.org/10.1186/ar2320