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SOX9 transduction of a human chondrocytic cell line identifies novel genes regulated in primary human chondrocytes and in osteoarthritis

The transcription factor SOX9 is important in maintaining the chondrocyte phenotype. To identify novel genes regulated by SOX9 we investigated changes in gene expression by microarray analysis following retroviral transduction with SOX9 of a human chondrocytic cell line (SW1353). From the results th...

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Detalles Bibliográficos
Autores principales: Tew, Simon R, Clegg, Peter D, Brew, Christopher J, Redmond, Colette M, Hardingham, Timothy E
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212576/
https://www.ncbi.nlm.nih.gov/pubmed/17935617
http://dx.doi.org/10.1186/ar2311