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Importance of spliceosomal RNP1 motif for intermolecular T-B cell spreading and tolerance restoration in lupus
We previously demonstrated the importance of the RNP1 motif-bearing region 131–151 of the U1-70K spliceosomal protein in the intramolecular T-B spreading that occurs in MRL/lpr lupus mice. Here, we analyze the involvement of RNP1 motif in the development and prevention of naturally-occurring intermo...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212579/ https://www.ncbi.nlm.nih.gov/pubmed/17963484 http://dx.doi.org/10.1186/ar2317 |