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Importance of spliceosomal RNP1 motif for intermolecular T-B cell spreading and tolerance restoration in lupus

We previously demonstrated the importance of the RNP1 motif-bearing region 131–151 of the U1-70K spliceosomal protein in the intramolecular T-B spreading that occurs in MRL/lpr lupus mice. Here, we analyze the involvement of RNP1 motif in the development and prevention of naturally-occurring intermo...

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Detalles Bibliográficos
Autores principales: Monneaux, Fanny, Parietti, Véronique, Briand, Jean-Paul, Muller, Sylviane
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212579/
https://www.ncbi.nlm.nih.gov/pubmed/17963484
http://dx.doi.org/10.1186/ar2317