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Tumor-infiltrating macrophages and dendritic cells in human colorectal cancer: relation to local regulatory T cells, systemic T-cell response against tumor-associated antigens and survival

INTRODUCTION: Although systemic T-cell responses against tumor antigens and tumor infiltration by T cells have been investigated in colorectal cancer (CRC), the initiation of spontaneous immune responses in situ is not well understood. Macrophages and dendritic cells (DC) play an important role as a...

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Detalles Bibliográficos
Autores principales: Nagorsen, Dirk, Voigt, Sabine, Berg, Erika, Stein, Harald, Thiel, Eckhard, Loddenkemper, Christoph
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212626/
https://www.ncbi.nlm.nih.gov/pubmed/18047662
http://dx.doi.org/10.1186/1479-5876-5-62