Gene array identification of Ipf1/Pdx1(-/- )regulated genes in pancreatic progenitor cells

BACKGROUND: The homeodomain transcription factor IPF1/PDX1 exerts a dual role in the pancreas; Ipf1/Pdx1 global null mutants fail to develop a pancreas whereas conditional inactivation of Ipf1/Pdx1 in β-cells leads to impaired β-cell function and diabetes. Although several putative target genes have...

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Detalles Bibliográficos
Autores principales: Svensson, Per, Williams, Cecilia, Lundeberg, Joakim, Rydén, Patrik, Bergqvist, Ingela, Edlund, Helena
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212654/
https://www.ncbi.nlm.nih.gov/pubmed/18036209
http://dx.doi.org/10.1186/1471-213X-7-129

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212654/
https://www.ncbi.nlm.nih.gov/pubmed/18036209
http://dx.doi.org/10.1186/1471-213X-7-129

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