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Constructing gene co-expression networks and predicting functions of unknown genes by random matrix theory

BACKGROUND: Large-scale sequencing of entire genomes has ushered in a new age in biology. One of the next grand challenges is to dissect the cellular networks consisting of many individual functional modules. Defining co-expression networks without ambiguity based on genome-wide microarray data is d...

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Detalles Bibliográficos
Autores principales: Luo, Feng, Yang, Yunfeng, Zhong, Jianxin, Gao, Haichun, Khan, Latifur, Thompson, Dorothea K, Zhou, Jizhong
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212665/
https://www.ncbi.nlm.nih.gov/pubmed/17697349
http://dx.doi.org/10.1186/1471-2105-8-299