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Positive Selection of B Cells Expressing Low Densities of Self-reactive BCRs

B cell tolerance or autoimmunity is determined by selective events. Negative selection of self-reactive B cells is well documented and proven. In contrast, positive selection of conventional B cells is yet to be firmly established. Here, we demonstrate that developing self-reactive B cells are not a...

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Detalles Bibliográficos
Autores principales: Gaudin, Emmanuelle, Hao, Yi, Rosado, Maria Manuela, Chaby, Richard, Girard, Robert, Freitas, António A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212726/
https://www.ncbi.nlm.nih.gov/pubmed/15024048
http://dx.doi.org/10.1084/jem.20030955