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PKCθ Signals Activation versus Tolerance In Vivo

Understanding the pathways that signal T cell tolerance versus activation is key to regulating immunity. Previous studies have linked CD28 and protein kinase C-θ (PKCθ) as a potential signaling pathway that influences T cell activation. Therefore, we have compared the responses of T cells deficient...

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Detalles Bibliográficos
Autores principales: Berg-Brown, Nancy N., Gronski, Matthew A., Jones, Russell G., Elford, Alisha R., Deenick, Elissa K., Odermatt, Bernhard, Littman, Dan R., Ohashi, Pamela S.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212730/
https://www.ncbi.nlm.nih.gov/pubmed/15024044
http://dx.doi.org/10.1084/jem.20031022