Immunoprevention of Basal Cell Carcinomas with Recombinant Hedgehog-interacting Protein

Basal cell carcinomas (BCCs) are driven by abnormal hedgehog signaling and highly overexpress several hedgehog target genes. We report here our use of one of these target genes, hedgehog-interacting protein (Hip1), as a tumor-associated antigen for immunoprevention of BCCs in Ptch1(+/−) mice treated...

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Detalles Bibliográficos
Autores principales: Vogt, Annika, Chuang, Pao-Tien, Hebert, Jennifer, Hwang, Jimmy, Lu, Ying, Kopelovich, Levy, Athar, Mohammad, Bickers, David R., Epstein, Ervin H.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212732/
https://www.ncbi.nlm.nih.gov/pubmed/15024045
http://dx.doi.org/10.1084/jem.20031190

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212732/
https://www.ncbi.nlm.nih.gov/pubmed/15024045
http://dx.doi.org/10.1084/jem.20031190

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