Ro/SSA autoantibodies directly bind cardiomyocytes, disturb calcium homeostasis, and mediate congenital heart block

Congenital heart block develops in fetuses after placental transfer of Ro/SSA autoantibodies from rheumatic mothers. The condition is often fatal and the majority of live-born children require a pacemaker at an early age. The specific antibody that induces the heart block and the mechanism by which...

Descripción completa

Detalles Bibliográficos
Autores principales: Salomonsson, Stina, Sonesson, Sven-Erik, Ottosson, Lars, Muhallab, Saad, Olsson, Tomas, Sunnerhagen, Maria, Kuchroo, Vijay K., Thorén, Peter, Herlenius, Eric, Wahren-Herlenius, Marie
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Brief Definitive Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212767/
https://www.ncbi.nlm.nih.gov/pubmed/15630133
http://dx.doi.org/10.1084/jem.20041859

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212767/
https://www.ncbi.nlm.nih.gov/pubmed/15630133
http://dx.doi.org/10.1084/jem.20041859

Ejemplares similares