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Conversion of CD4(+) CD25(−) cells into CD4(+) CD25(+) regulatory T cells in vivo requires B7 costimulation, but not the thymus
The CD4(+) CD25(+) regulatory T cells play a critical role in controlling autoimmunity, but little is known about their development and maintenance. In this study, we investigated whether CD4(+) CD25(−) cells can convert to CD4(+) CD25(+) regulatory T cells in vivo under natural conditions. CD4(+) C...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2005
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212775/ https://www.ncbi.nlm.nih.gov/pubmed/15630140 http://dx.doi.org/10.1084/jem.20041201 |