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Conversion of CD4(+) CD25(−) cells into CD4(+) CD25(+) regulatory T cells in vivo requires B7 costimulation, but not the thymus

The CD4(+) CD25(+) regulatory T cells play a critical role in controlling autoimmunity, but little is known about their development and maintenance. In this study, we investigated whether CD4(+) CD25(−) cells can convert to CD4(+) CD25(+) regulatory T cells in vivo under natural conditions. CD4(+) C...

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Detalles Bibliográficos
Autores principales:	Liang, Shuang, Alard, Pascale, Zhao, Yuan, Parnell, Sarah, Clark, Sherry L., Kosiewicz, Michele M.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2005
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212775/ https://www.ncbi.nlm.nih.gov/pubmed/15630140 http://dx.doi.org/10.1084/jem.20041201

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