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Do developing B cells need antigen?

Just as potentially useful T cells are positively selected by MHC–peptide complexes in the thymus, it has been proposed that self or commensal bacterial epitopes might select B cell populations with the capacity to recognize polysaccharide or protein structures on pathogens. Recent studies indicate...

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Detalles Bibliográficos
Autores principales: Weill, Jean-Claude, Reynaud, Claude-Agnès
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212778/
https://www.ncbi.nlm.nih.gov/pubmed/15630132
http://dx.doi.org/10.1084/jem.20042111