Identification of poxvirus CD8(+) T cell determinants to enable rational design and characterization of smallpox vaccines

The large size of poxvirus genomes has stymied attempts to identify determinants recognized by CD8(+) T cells and greatly impeded development of mouse smallpox vaccination models. Here, we use a vaccinia virus (VACV) expression library containing each of the predicted 258 open reading frames to iden...

Descripción completa

Detalles Bibliográficos
Autores principales: Tscharke, David C., Karupiah, Gunasegaran, Zhou, Jie, Palmore, Tara, Irvine, Kari R., Haeryfar, S.M. Mansour, Williams, Shanicka, Sidney, John, Sette, Alessandro, Bennink, Jack R., Yewdell, Jonathan W.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212779/
https://www.ncbi.nlm.nih.gov/pubmed/15623576
http://dx.doi.org/10.1084/jem.20041912

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212779/
https://www.ncbi.nlm.nih.gov/pubmed/15623576
http://dx.doi.org/10.1084/jem.20041912

Ejemplares similares