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Identification of poxvirus CD8(+) T cell determinants to enable rational design and characterization of smallpox vaccines
The large size of poxvirus genomes has stymied attempts to identify determinants recognized by CD8(+) T cells and greatly impeded development of mouse smallpox vaccination models. Here, we use a vaccinia virus (VACV) expression library containing each of the predicted 258 open reading frames to iden...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2005
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212779/ https://www.ncbi.nlm.nih.gov/pubmed/15623576 http://dx.doi.org/10.1084/jem.20041912 |