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High frequency of antitumor T cells in the blood of melanoma patients before and after vaccination with tumor antigens

After vaccination of melanoma patients with MAGE antigens, we observed that even in the few patients showing tumor regression, the frequency of anti-vaccine T cells in the blood was often either undetectable or <10(−5) of CD8 T cells. This frequency being arguably too low for these cells to be so...

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Detalles Bibliográficos
Autores principales: Germeau, Catherine, Ma, Wenbin, Schiavetti, Francesca, Lurquin, Christophe, Henry, Emmanuelle, Vigneron, Nathalie, Brasseur, Francis, Lethé, Bernard, De Plaen, Etienne, Velu, Thierry, Boon, Thierry, Coulie, Pierre G.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212796/
https://www.ncbi.nlm.nih.gov/pubmed/15657293
http://dx.doi.org/10.1084/jem.20041379