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High frequency of antitumor T cells in the blood of melanoma patients before and after vaccination with tumor antigens
After vaccination of melanoma patients with MAGE antigens, we observed that even in the few patients showing tumor regression, the frequency of anti-vaccine T cells in the blood was often either undetectable or <10(−5) of CD8 T cells. This frequency being arguably too low for these cells to be so...
Autores principales: | , , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212796/ https://www.ncbi.nlm.nih.gov/pubmed/15657293 http://dx.doi.org/10.1084/jem.20041379 |