The Linkage of Innate to Adaptive Immunity via Maturing Dendritic Cells In Vivo Requires CD40 Ligation in Addition to Antigen Presentation and CD80/86 Costimulation

Dendritic cell (DC) maturation is an innate response that leads to adaptive immunity to coadministered proteins. To begin to identify underlying mechanisms in intact lymphoid tissues, we studied α-galactosylceramide. This glycolipid activates innate Vα14(+) natural killer T cell (NKT) lymphocytes, w...

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Detalles Bibliográficos
Autores principales: Fujii, Shin-ichiro, Liu, Kang, Smith, Caroline, Bonito, Anthony J., Steinman, Ralph M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212806/
https://www.ncbi.nlm.nih.gov/pubmed/15197224
http://dx.doi.org/10.1084/jem.20040317

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212806/
https://www.ncbi.nlm.nih.gov/pubmed/15197224
http://dx.doi.org/10.1084/jem.20040317

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