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Toll-like Receptor 9–Dependent and –Independent Dendritic Cell Activation by Chromatin–Immunoglobulin G Complexes

Dendritic cell (DC) activation by nucleic acid–containing immunoglobulin (Ig)G complexes has been implicated in systemic lupus erythematosus (SLE) pathogenesis. However, the mechanisms responsible for activation and subsequent disease induction are not completely understood. Here we show that murine...

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Detalles Bibliográficos
Autores principales: Boulé, Melissa W., Broughton, Courtney, Mackay, Fabienne, Akira, Shizuo, Marshak-Rothstein, Ann, Rifkin, Ian R.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212813/
https://www.ncbi.nlm.nih.gov/pubmed/15197227
http://dx.doi.org/10.1084/jem.20031942