Cargando…

SOCS1 Is a Suppressor of Liver Fibrosis and Hepatitis-induced Carcinogenesis

Hepatocellular carcinomas (HCCs) mainly develop from liver cirrhosis and severe liver fibrosis that are established with long-lasting inflammation of the liver. Silencing of the suppressor of the cytokine signaling-1 (SOCS1) gene, a negative regulator of cytokine signaling, by DNA methylation has be...

Descripción completa

Detalles Bibliográficos
Autores principales: Yoshida, Takafumi, Ogata, Hisanobu, Kamio, Masaki, Joo, Akiko, Shiraishi, Hiroshi, Tokunaga, Yoko, Sata, Michio, Nagai, Hisaki, Yoshimura, Akihiko
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212816/
https://www.ncbi.nlm.nih.gov/pubmed/15197228
http://dx.doi.org/10.1084/jem.20031675