Intratumor depletion of CD4(+) cells unmasks tumor immunogenicity leading to the rejection of late-stage tumors

Tumor environment can be critical for preventing the immunological destruction of antigenic tumors. We have observed a selective accumulation of CD4(+)CD25(+) T cells inside tumors. In a murine fibrosarcoma L(d)-expressing Ag104, these cells made up the majority of tumor-infiltrating lymphocytes at...

Descripción completa

Detalles Bibliográficos
Autores principales: Yu, Ping, Lee, Youjin, Liu, Wenhua, Krausz, Thomas, Chong, Anita, Schreiber, Hans, Fu, Yang-Xin
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212829/
https://www.ncbi.nlm.nih.gov/pubmed/15753211
http://dx.doi.org/10.1084/jem.20041684

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212829/
https://www.ncbi.nlm.nih.gov/pubmed/15753211
http://dx.doi.org/10.1084/jem.20041684

Ejemplares similares