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Intratumor depletion of CD4(+) cells unmasks tumor immunogenicity leading to the rejection of late-stage tumors
Tumor environment can be critical for preventing the immunological destruction of antigenic tumors. We have observed a selective accumulation of CD4(+)CD25(+) T cells inside tumors. In a murine fibrosarcoma L(d)-expressing Ag104, these cells made up the majority of tumor-infiltrating lymphocytes at...
| Autores principales: | , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2005
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212829/ https://www.ncbi.nlm.nih.gov/pubmed/15753211 http://dx.doi.org/10.1084/jem.20041684 |