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Mycobacterial catalase–peroxidase is a tissue antigen and target of the adaptive immune response in systemic sarcoidosis

Sarcoidosis is a disease of unknown etiology characterized by noncaseating epithelioid granulomas, oligoclonal CD4(+) T cell infiltrates, and immune complex formation. To identify pathogenic antigens relevant to immune-mediated granulomatous inflammation in sarcoidosis, we used a limited proteomics...

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Detalles Bibliográficos
Autores principales: Song, Zhimin, Marzilli, Lisa, Greenlee, Brian M., Chen, Edward S., Silver, Richard F., Askin, Frederic B., Teirstein, Alvin S., Zhang, Ying, Cotter, Robert J., Moller, David R.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212832/
https://www.ncbi.nlm.nih.gov/pubmed/15753209
http://dx.doi.org/10.1084/jem.20040429