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Defective B cell tolerance checkpoints in systemic lupus erythematosus

A cardinal feature of systemic lupus erythematosus (SLE) is the development of autoantibodies. The first autoantibodies described in patients with SLE were those specific for nuclei and DNA, but subsequent work has shown that individuals with this disease produce a panoply of different autoantibodie...

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Detalles Bibliográficos
Autores principales: Yurasov, Sergey, Wardemann, Hedda, Hammersen, Johanna, Tsuiji, Makoto, Meffre, Eric, Pascual, Virginia, Nussenzweig, Michel C.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212839/
https://www.ncbi.nlm.nih.gov/pubmed/15738055
http://dx.doi.org/10.1084/jem.20042251