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Defective B cell tolerance checkpoints in systemic lupus erythematosus
A cardinal feature of systemic lupus erythematosus (SLE) is the development of autoantibodies. The first autoantibodies described in patients with SLE were those specific for nuclei and DNA, but subsequent work has shown that individuals with this disease produce a panoply of different autoantibodie...
Autores principales: | Yurasov, Sergey, Wardemann, Hedda, Hammersen, Johanna, Tsuiji, Makoto, Meffre, Eric, Pascual, Virginia, Nussenzweig, Michel C. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212839/ https://www.ncbi.nlm.nih.gov/pubmed/15738055 http://dx.doi.org/10.1084/jem.20042251 |
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