Regulation of TCR δ and α repertoires by local and long-distance control of variable gene segment chromatin structure

Murine Tcrd and Tcra gene segments reside in a single genetic locus and undergo recombination in CD4(−)CD8(−) (double negative [DN]) and CD4(+)CD8(+) (double positive [DP]) thymocytes, respectively. TcraTcrd locus variable gene segments are subject to complex regulation. Only a small subset of ∼100...

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Detalles Bibliográficos
Autores principales: Hawwari, Abbas, Krangel, Michael S.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Brief Definitive Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212846/
https://www.ncbi.nlm.nih.gov/pubmed/16087716
http://dx.doi.org/10.1084/jem.20050680

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212846/
https://www.ncbi.nlm.nih.gov/pubmed/16087716
http://dx.doi.org/10.1084/jem.20050680

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