IL-4 receptor expression on CD8(+) T cells is required for the development of protective memory responses against liver stages of malaria parasites

IL-4 receptor (IL-4R)-deficient CD8+ T cells specific for the circumsporozoite protein of Plasmodium yoelii develop a severely impaired memory response after priming with parasites. Memory CD8(+) T cells lacking the IL-4R are unable to establish a stable population residing in nonlymphoid organs, al...

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Detalles Bibliográficos
Autores principales: Morrot, Alexandre, Hafalla, Julius C.R., Cockburn, Ian A., Carvalho, Luzia H., Zavala, Fidel
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212849/
https://www.ncbi.nlm.nih.gov/pubmed/16087712
http://dx.doi.org/10.1084/jem.20042463

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212849/
https://www.ncbi.nlm.nih.gov/pubmed/16087712
http://dx.doi.org/10.1084/jem.20042463

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