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IL-4 receptor expression on CD8(+) T cells is required for the development of protective memory responses against liver stages of malaria parasites
IL-4 receptor (IL-4R)-deficient CD8+ T cells specific for the circumsporozoite protein of Plasmodium yoelii develop a severely impaired memory response after priming with parasites. Memory CD8(+) T cells lacking the IL-4R are unable to establish a stable population residing in nonlymphoid organs, al...
Autores principales: | Morrot, Alexandre, Hafalla, Julius C.R., Cockburn, Ian A., Carvalho, Luzia H., Zavala, Fidel |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212849/ https://www.ncbi.nlm.nih.gov/pubmed/16087712 http://dx.doi.org/10.1084/jem.20042463 |
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