IL-18 with IL-2 protects against Strongyloides venezuelensis infection by activating mucosal mast cell–dependent type 2 innate immunity

C57BL/6 (B6) and B6 background STAT6(−/−) mice pretreated with IL-18 plus IL-2 showed prominent intestinal mastocytosis and rapidly expelled implanted adult worms of the gastrointestinal nematode Strongyloides venezuelensis. In contrast, identically pretreated mast cell–deficient W/W(v) mice failed...

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Detalles Bibliográficos
Autores principales: Sasaki, Yuki, Yoshimoto, Tomohiro, Maruyama, Haruhiko, Tegoshi, Tatsuya, Ohta, Nobuo, Arizono, Naoki, Nakanishi, Kenji
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212862/
https://www.ncbi.nlm.nih.gov/pubmed/16129701
http://dx.doi.org/10.1084/jem.20042202

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212862/
https://www.ncbi.nlm.nih.gov/pubmed/16129701
http://dx.doi.org/10.1084/jem.20042202

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