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A novel glyco-conjugate vaccine against fungal pathogens

To generate a vaccine to protect against a variety of human pathogenic fungi, we conjugated laminarin (Lam), a well-characterized but poorly immunogenic β-glucan preparation from the brown alga Laminaria digitata, with the diphtheria toxoid CRM197, a carrier protein used in some glyco-conjugate bact...

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Detalles Bibliográficos
Autores principales: Torosantucci, Antonella, Bromuro, Carla, Chiani, Paola, De Bernardis, Flavia, Berti, Francesco, Galli, Chiara, Norelli, Francesco, Bellucci, Cinzia, Polonelli, Luciano, Costantino, Paolo, Rappuoli, Rino, Cassone, Antonio
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212864/
https://www.ncbi.nlm.nih.gov/pubmed/16147975
http://dx.doi.org/10.1084/jem.20050749