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A novel glyco-conjugate vaccine against fungal pathogens
To generate a vaccine to protect against a variety of human pathogenic fungi, we conjugated laminarin (Lam), a well-characterized but poorly immunogenic β-glucan preparation from the brown alga Laminaria digitata, with the diphtheria toxoid CRM197, a carrier protein used in some glyco-conjugate bact...
Autores principales: | Torosantucci, Antonella, Bromuro, Carla, Chiani, Paola, De Bernardis, Flavia, Berti, Francesco, Galli, Chiara, Norelli, Francesco, Bellucci, Cinzia, Polonelli, Luciano, Costantino, Paolo, Rappuoli, Rino, Cassone, Antonio |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212864/ https://www.ncbi.nlm.nih.gov/pubmed/16147975 http://dx.doi.org/10.1084/jem.20050749 |
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