Type I interferons act directly on CD8 T cells to allow clonal expansion and memory formation in response to viral infection

T cell expansion and memory formation are generally more effective when elicited by live organisms than by inactivated vaccines. Elucidation of the underlying mechanisms is important for vaccination and therapeutic strategies. We show that the massive expansion of antigen-specific CD8 T cells that o...

Descripción completa

Detalles Bibliográficos
Autores principales: Kolumam, Ganesh A., Thomas, Sunil, Thompson, Lucas J., Sprent, Jonathan, Murali-Krishna, Kaja
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212878/
https://www.ncbi.nlm.nih.gov/pubmed/16129706
http://dx.doi.org/10.1084/jem.20050821

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212878/
https://www.ncbi.nlm.nih.gov/pubmed/16129706
http://dx.doi.org/10.1084/jem.20050821

Ejemplares similares